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PLOS Genetics, eLife, Nat Rev Mol Cell Biol, Ann Oncol, EMBO Mol Med: our 5 latest publications

Category: Highlighted publications at the CRCM

 

 

 

Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis.

Cartier-Michaud A, Bailly AL, Betzi S, Shi X, Lissitzky JC, Zarubica A, Sergé A, Roche P, Lugari A, Hamon V, Bardin F, Derviaux C, Lembo F, Audebert S, Marchetto S, Durand B, Borg JP, Shi N, Morelli X, Aurrand-Lions M.

PLoS Genet. 2017 Jun 15;13(6):e1006803. doi: 10.1371/journal.pgen.1006803. eCollection 2017 Jun.

 

journals.plos.org/plosgenetics/article

Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining

Davide Normanno, Aurélie Négrel, Abinadabe J. de Melo, Stéphane Betzi, Katheryn Meek, and Mauro Modesti 

eLife 2017;10.7554/eLife.22900

dx.doi.org/10.7554/eLife.22900Control of structure-specific endonucleases to maintain genome stability


Pierre-Marie Dehé
 Pierre-Henri L. Gaillard

Nature Reviews Molecular Cell Biology (2017) doi:10.1038/nrm.2016.177

www.nature.com/nrm/journal/vaop/ncurrent/abs/nrm.2016.177.html

Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination


Ineke Brouwer, Hongshan Zhang, Andrea Candelli, Davide Normanno, Erwin J.G. Peterman, Gijs J.L. Wuite, Mauro Modesti

Cell Reports 18 (2017) pp. 2845-2853

dx.doi.org/10.1016/j.celrep.2017.02.068

www.sciencedirect.com/science/article/pii/S2211124717302851

 

Nectin-4: a new prognostic biomarker for efficient therapeutic targeting of primary and metastatic triple-negative breast cancer.

M-Rabet M, Cabaud OJosselin EFinetti PCastellano RFarina AAgavnian-Couquiaud ESaviane GCollette YViens PGonçalves AGinestier CCharafe-Jauffret EBirnbaum DOlive DBertucci FLopez M.

Ann. Oncol., 2016 Dec 20. pii: mdw678.

https://www.ncbi.nlm.nih.gov/pubmed/?term=Nectin-4%3A+a+new+prognostic+biomarker+for+efficient+therapeutic+targeting+of+primary+and+metastatic+triple-negative+breast+cancer.

Gene Expression Profiling of Patient-Derived Pancreatic Cancer Xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: Implications to individualized medicine efforts.

Bian B, Bigonnet M, Gayet O, Loncle C, Maignan A, Gilabert M, Moutardier V, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Ouaissi M, Secq V, Poizat F, Nicolle R, Blum Y, Marisa L, Rubis M, Raou JL, Bradner JE, Qi J, Lomberk G, Urrutia R, Saul A, Dusetti N, Iovanna J.

EMBO Molecular Medicine, 2017. doi: 
10.15252/emmm.201606975

embomolmed.embopress.org/cgi/doi/10.15252/emmm.201606975